A potential treatment for Alzheimer’s disease has been successful in mice using synthetic molecules.
Posted by TeeJay Small | issued
The first trial appeared to cure Alzheimer’s disease in mice, and new treatments for Alzheimer’s disease are now being developed, according to a recent scientific journal article. biomedi central. The trial, conducted through 2022 by a team of Israeli scientists, reportedly restored full cognitive ability in 30 mice with Alzheimer’s disease using a synthetic molecule. The road to developing a treatment suitable for humanity is long and difficult, but these trials are an excellent first step toward eradicating the disease in the future.
The peer-reviewed study focuses on a new approach to developing treatments for Alzheimer’s disease, and Ben-Gurion University scientists say the approach is highly effective in the mice they studied. there is Although existing treatments exist to manage and reduce the spread of Alzheimer’s disease in the brain, Professor Varda Shoshan-Vermatz and her team have begun trials to address plaque buildup in the brain. The molecule developed by the research team did not do much to physically remove or reduce plaque from the brains of experimental mice, but the results appeared to be overwhelmingly positive, with 30 mice participating in the study. All were cured.
Alzheimer’s disease is commonly described as a progressive impairment that interferes with memory and other cognitive brain functions. With more than 3 million new cases in the United States each year, many develop the disease as they get older and are forced to watch their friends and loved ones deteriorate. It’s getting worse. Thanks to the mitochondrial molecule developed by Shoshan Vermatz and her team, we seem to be one step closer to achieving a long-sought cure for Alzheimer’s disease, and it’s far from too early.
Of course, mitochondria are the powerhouses of cells, providing energy to individual cells such as those found in the brain. When plaque buildup causes blockage in an Alzheimer’s disease-infected brain, these cells slow down and stop, requiring significantly more power to cross the infected area. That’s where this molecule comes in, giving cells extra power to restore function and serve as the closest thing to a treatment for Alzheimer’s that can be achieved today.
Other published research focused on mitochondria and their increased energy needs, even though mitochondrial dysfunction has been a major obstacle to all other attempts to develop treatments for Alzheimer’s disease. is currently not available. The Ben-Gurion University team has invaluable scientific brains in this regard. Their method of targeting plaque accumulation led to the discovery that foreign molecules could act as backup batteries for dying cells.
In addition, the research team discovered a protein segment that plays an important role in regulating the energy function of cells that is diagnostic of Alzheimer’s disease. Although it is still years away from developing a full-fledged Alzheimer’s disease cure and readying it for clinical trials in humans, this discovery provides insight into how and why the Alzheimer’s diseased brain behaves that way. There is no doubt that it will be an important stepping stone in understanding what to do. The team founded a startup called Tamarix, which aims to take the next step in eradicating the disease from the millions of people who suffer from it worldwide.